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词条 EEF-1
释义

  1. See also

  2. References

  3. External links

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eEF-1 is a eukaryotic elongation factor.

Its α and βγ subunits act as counterparts to EF-Tu and EF-Ts, respectively

Genes include:

  • EEF1A1, EEF1A2, EEF1A3
  • EEF1B1, EEF1B2, EEF1B3, EEF1B4
  • EEF1D, EEF1E1, EEF1G

Various species of green algae, red algae, chromalveolates, and fungi lack the EF-1α gene but instead possess a related gene called EFL (elongation factor-like). Although its function has not been studied in depth, it appears to be similar to EF-1α.

Only two organisms are known to have both EF-1α and EFL: the fungus Basidiobolus and the diatom Thalassiosira. The evolutionary history of EFL is unclear. It may have arisen one or more times followed by loss of EFL or EF-1α. The presence in three diverse eukaryotic groups (fungi, chromalveolates, and archaeplastida) is supposed to be the result of two or more horizontal gene transfer events.[1]

See also

  • Eukaryotic translation

References

1. ^{{citation | journal = BMC Evol. Biol. | year = 2009 | volume = 9 | pages = 39 | doi = 10.1186/1471-2148-9-39 | pmc = 2652445 | title = Gain and loss of elongation factor genes in green algae |author1=Ellen Cocquyt |author2=Heroen Verbruggen |author3=Frederik Leliaert |author4=Frederick W Zechman |author5=Koen Sabbe |author6=Olivier De Clerck | pmid=19216746}}

External links

  • {{MeshName|Peptide+Elongation+Factor+1}}
{{GeneticTranslation}}{{GTPases}}

2 : Protein biosynthesis|Eukaryote genes

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