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词条 Hydrocortisone aceponate
释义

  1. References

{{See also|hydrocortisone}}{{Drugbox
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| IUPAC_name = (11β)-21-(acetyloxy)-11-hydroxy-3,20-dioxopregn-4-en-17-yl propionate
| image = Hydrocortisone aceponate.svg
| tradename =
| Drugs.com = {{drugs.com|monograph|hydrocortisone}}
| pregnancy_AU =
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| legal_AU =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration = Topical
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 74050-20-7
| ATC_prefix = D07
| ATC_suffix = AC16
| PubChem = 68921
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2106309
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 2340UP1L2G
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D06876
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| C=26 | H=36 | O=7
| molecular_weight = 460.560 g/mol
| smiles = CCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)C
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| StdInChI = 1S/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1
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Hydrocortisone aceponate is a corticosteroid that is used in form of creams for the treatment of various dermatoses (skin conditions).[1] It is an ester of hydrocortisone (cortisol) with acetic acid and propionic acid.

References

1. ^{{Cite journal | last1 = Baghel | first1 = V. | last2 = Mukhopadhyay | first2 = A. | doi = 10.4103/0378-6323.69093 | title = A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients | journal = Indian Journal of Dermatology, Venereology and Leprology | volume = 76 | issue = 5 | pages = 591 | year = 2010 | pmid = 20827017 | pmc = }}
{{Glucocorticoids}}{{Glucocorticoidics}}{{DEFAULTSORT:Hydrocortisone Aceponate}}{{dermatologic-drug-stub}}

4 : Corticosteroid esters|Corticosteroids|Propionate esters|Acetate esters

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