词条 | Hydrocortisone aceponate |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 407390255 | IUPAC_name = (11β)-21-(acetyloxy)-11-hydroxy-3,20-dioxopregn-4-en-17-yl propionate | image = Hydrocortisone aceponate.svg | tradename = | Drugs.com = {{drugs.com|monograph|hydrocortisone}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Topical | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 74050-20-7 | ATC_prefix = D07 | ATC_suffix = AC16 | PubChem = 68921 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2106309 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 2340UP1L2G | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D06876 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 62148 | C=26 | H=36 | O=7 | molecular_weight = 460.560 g/mol | smiles = CCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)C | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = MFBMYAOAMQLLPK-FZNHGJLXSA-N }} Hydrocortisone aceponate is a corticosteroid that is used in form of creams for the treatment of various dermatoses (skin conditions).[1] It is an ester of hydrocortisone (cortisol) with acetic acid and propionic acid. References1. ^{{Cite journal | last1 = Baghel | first1 = V. | last2 = Mukhopadhyay | first2 = A. | doi = 10.4103/0378-6323.69093 | title = A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients | journal = Indian Journal of Dermatology, Venereology and Leprology | volume = 76 | issue = 5 | pages = 591 | year = 2010 | pmid = 20827017 | pmc = }} {{Glucocorticoids}}{{Glucocorticoidics}}{{DEFAULTSORT:Hydrocortisone Aceponate}}{{dermatologic-drug-stub}} 4 : Corticosteroid esters|Corticosteroids|Propionate esters|Acetate esters |
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