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词条 Mesangium
释义

  1. References

  2. Further reading

  3. External links

{{Nofootnotes|article|date=February 2018}}{{Infobox anatomy
| Name = Mesangium
| Latin =
| Image = Renal corpuscle-en.svg
| Caption = Renal corpuscle showing the mesangial cells. The mesangium is the purple structure inside the glomerulus between the capillaries and extending outside the glomerulus.
| Image2 =
| Caption2 =
| IsPartOf =
| Components =
| Artery =
| Vein =
}}

In the glomerulus of the kidney, the mesangium is a structure associated with the capillaries. It is continuous with the smooth muscles of the arterioles. It is outside the capillary lumen, but surrounded by capillaries. It is in the middle (meso) between the capillaries (angis). It is contained by the basement membrane, which surrounds both the capillaries and the mesangium.

This term is often used interchangeably with mesangial cell, but in this context refers specifically to the intraglomerular mesangial cells. These cells are phagocytic and secrete the amorphous basement membrane-like material known as the mesangial matrix. They are typically separated from the lumen of the capillaries by endothelial cells.

References

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Further reading

  • {{cite book |last1=Nielsen |first1=S. |last2=Kwon |first2=T.H. |last3=Fenton |first3=R.A. |last4=Praetorious |first4=J. |chapter=Anatomy of the Kidney |editor1-last=Rector |editor1-first=F. C. |editor2-last=Brenner |editor2-first=B. M. |title=Brenner & Rector's the kidney |edition=9th |location=Philadelphia |publisher=Elsevier Saunders |year=2012 |pages=31–93 |volume=1 |isbn=978-1-4160-6193-9 }}
  • {{cite journal |pmid=7787139 |url=http://jasn.asnjournals.org/cgi/pmidlookup?view=long&pmid=7787139 |year=1995 |author1=Kriz |first1=W |title=Structure-stabilizing forces in the glomerular tuft |journal=Journal of the American Society of Nephrology |volume=5 |issue=10 |pages=1731–9 |last2=Elger |first2=M |last3=Mundel |first3=P |last4=Lemley |first4=K. V }}
  • {{cite journal |doi=10.1038/ki.1996.229 |pmid=8743459 |title=Roles of the mesangium in glomerular function |journal=Kidney International |volume=49 |issue=6 |pages=1583–5 |year=1996 |last1=Schlöndorff |first1=Detlef }}
  • {{cite journal |doi=10.14814/phy2.12537 |pmid=26438731 |pmc=4632944 |title=Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival |journal=Physiological Reports |volume=3 |issue=10 |pages=e12537 |year=2015 |last1=Phua |first1=Yu Leng |last2=Chu |first2=Jessica Y. S |last3=Marrone |first3=April K |last4=Bodnar |first4=Andrew J |last5=Sims‐Lucas |first5=Sunder |last6=Ho |first6=Jacqueline }}
{{refend}}

External links

  • {{DorlandsDict|five/000064972|Mesangium}}
{{Kidney}}{{genitourinary-stub}}

1 : Kidney anatomy

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