词条 | Donald Metcalf |
释义 |
| name = Donald Metcalf | image = | image_size = 180px | birth_date = 26 February 1929 | birth_place = | death_date = {{dda|df=y|2014|12|15|1929|2|26}}[1][2] | death_place = Melbourne, Australia | death_cause = | nationality = Australia | field = medicine | work_institution =Walter and Eliza Hall Institute of Medical Research | alma_mater = | known_for =discovering the colony stimulating factors | prizes = {{Plainlist|
| website = {{URL|http://www.wehi.edu.au/about-history/notable-scientists/professor-don-metcalf}} }}Donald Metcalf AC FRS[3] FAA (26 February 1929 – 15 December 2014) was an Australian medical researcher who spent most of his career at the Walter and Eliza Hall Institute of Medical Research in Melbourne. In 1954 he received the Carden Fellowship from the Anti-Cancer Council of Victoria; while he officially retired in 1996, he continued working and held his fellowship until his retirement in December 2014.[2][4][8][5] Education, research and careerMetcalf studied medicine at the University of Sydney, and had his first experience of medical research in the laboratory of Professor Patrick de Burgh. In 1954 Metcalf was awarded a Carden Fellowship from the Anti-Cancer Council of Victoria at the Walter and Eliza Hall Institute of Medical Research. There he initially studied virology and leukemia, later transitioning to hematology.[6] Metcalf's pioneering research revealed the control of blood cell formation and the role of hematopoietic cytokines. In the 1960s he developed techniques to culture blood cells, which led to the discovery of colony-stimulating factors (CSFs), including macrophage colony-stimulating factor, granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor. CSFs are cytokines that control white blood cell formation and are responsible for resistance to infection. CSFs are now widely used to boost the immune system for patients receiving chemotherapy, and to mobilise blood stem cells for transplants. Awards and honoursIn the Australia Day Honours of 1976, he was named an Officer of the Order of Australia (AO).[7] In the Queen's Birthday Honours of 1993, he was promoted to Companion of the Order (AC).[8] Metcalf has been awarded many international prizes including
In Australia Metcalf has received the 1985 James Cook Medal, the 2000 Victoria Prize, the 2001 Prime Minister's Prize for Science and the Centenary Medal.[9] Personal lifeMetcalf has four daughters and six grandchildren. He lived in Melbourne with his wife, Josephine, and died on 15 December 2014 following pancreatic cancer.[10] His autobiography Summon up the Blood: In dogged pursuit of the blood cell regulators was published in 2000.[11] References1. ^{{Cite journal | pmid = 25631437| year = 2015| author1 = Hilton| first1 = Doug| authorlink1 = Doug Hilton| title = Donald Metcalf (1929-2014) Discoverer of hormones that regulate blood-cell proliferation| journal = Nature| volume = 517| issue = 7536| pages = 554| doi = 10.1038/517554a}} 2. ^1 2 {{cite journal|last1=Nicola|first1=Nicos A.|title=Donald Metcalf AC. 26 February 1929 — 15 December 2014|journal=Biographical Memoirs of Fellows of the Royal Society|year=2016|publisher=Royal Society|location=London|doi=10.1098/rsbm.2016.0013}} 3. ^1 {{cite web|archiveurl=https://web.archive.org/web/20151117022259/https://royalsociety.org/people/donald-metcalf-11946/ |archivedate=2015-11-17 |url=https://royalsociety.org/people/donald-metcalf-11946/ |publisher=Royal Society |location=London |website=royalsociety.org |title=Professor Donald Metcalf AC FRS |author=Anon |year=1983 }} One or more of the preceding sentences incorporates text from the royalsociety.org website where: {{quote|"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --{{cite web|url=https://royalsociety.org/about-us/terms-conditions-policies/ |title=Royal Society Terms, conditions and policies |accessdate=2016-03-09 |deadurl=bot: unknown |archiveurl=https://web.archive.org/web/20150925220834/https://royalsociety.org/about-us/terms-conditions-policies/ |archivedate=2015-09-25 |df= }}}} 4. ^{{cite web |url=http://www.cancervic.org.au/research/researchers/donald-metcalf.html |title=Prof. Donald Metcalf Carden Fellow |author= |date=2014 |website=The Cancer Council Victoria|accessdate=15 December 2014}} 5. ^{{cite web|url=http://www.wehi.edu.au/faculty_members/professor_don_metcalf|title=Professor Don Metcalf lab page|publisher=Walter and Eliza Hall Institute of Medical Research|website=wehi.edu.au}} 6. ^{{cite web|url=http://www.science.org.au/scientists/interviews/m/dm.html |title=Professor Don Metcalf |publisher=Australian Academy of Science |deadurl=unfit |archiveurl=https://web.archive.org/web/20110607122522/http://www.science.org.au/scientists/interviews/m/dm.html |archivedate=7 June 2011 }} 7. ^It's an Honour: AO 8. ^It's an Honour: AC 9. ^It's an Honour: Centenary Medal 10. ^Douglas Hilton, Warren Alexander and Nicos Nicola. "A tribute to Professor Donald Metcalf", Walter and Eliza Hall Institute of Medical Research, 15 December 2014. 11. ^1 AlphaMed Press, Dayton, Ohio, USA, 2000. {{ISBN|1-880854-28-7}} Further reading
12 : 1929 births|Members of the United States National Academy of Sciences|2014 deaths|Australian physiologists|Australian immunologists|Fellows of the Royal Society|Fellows of the Australian Academy of Science|Royal Medal winners|Companions of the Order of Australia|Walter and Eliza Hall Institute of Medical Research alumni|Sydney Medical School alumni|Recipients of the Lasker-DeBakey Clinical Medical Research Award |
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