Donald Payne may refer to:

• Donald G. Payne (1924-2018), English author
• Donald M. Payne (1934–2012), former U.S. Representative from New Jersey, father of Donald Payne, Jr.
• Donald Payne Jr. (born 1958), current U.S. Representative from New Jersey, son of Donald M. Payne
• Donald Payne (British Army soldier) (born 1970), British soldier who became his country's first convicted war criminal during his tour in Iraq
• Don Payne (writer) (1964–2013), American writer and producer
• Don Payne (musician) (1933–2017), American jazz bassist
• Donald Payne (American football) (born 1994), American football player

• Phosphogluconate oxidative pathway
• Phosphoglycerate
• Phosphoglycerate dehydrogenase
• Phosphoglycerate (disambiguation)
• Phosphoglycerate kinase (GTP)
• Phosphoglycerate phosphatase
• Phosphoglyceric acid
• Phosphoglycerol geranylgeranyltransferase
• Phosphoglycolate phosphatase
• Phosphoimager
• Phosphoinositide 3-kinase inhibitor
• Phosphoinositide 5-phosphatase
• Phosphoinositide-dependent kinase-1
• Phosphoinositides
• Phospholambin
• Phospholane
• Phospholemman
• Phospholine
• Phospholipase A-2-activating protein
• Phospholipase A (disambiguation)
• Phospholipase C
• Phospholipase c gamma
• Phospholipase c pathway
• Phospholipase C pathway
• Phospholipid acyltransferase