| 词条 | Dyslipidemia | |||||||||||||||||||
| 释义 |
| name = Dyslipidemia | image = | caption = | field = Cardiology | | pronounce = | synonyms = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood. In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle. Prolonged elevation of insulin levels can also lead to dyslipidemia. Likewise, increased levels of O-GlcNAc transferase (OGT) may cause dyslipidemia.{{Citation needed|date=March 2017}} ClassificationPhysicians and basic researchers classify dyslipidemias in two distinct ways:
Fredrickson Classification:[1] {{for|a more detailed version|Hyperlipidemia#Classification}}
Types
ScreeningTesting the general population under the age of 40 without symptoms is of unclear benefit.[2][3] ManagementStatinsFibratesEzetimibe{{citation needed|date=April 2019}} References1. ^Fredrickson DS, Lees RS. A system for phenotyping hyperlipoproteinemia. Circulation 1965;31:321-327. {{Medical resources2. ^{{cite journal|title=Screening for Lipid Disorders in Children and Adolescents|journal=JAMA|volume=316|issue=6|pages=625–33|date=August 9, 2016|doi=10.1001/jama.2016.9852|pmid=27532917|last1=Bibbins-Domingo|first1=Kirsten|last2=Grossman|first2=David C.|last3=Curry|first3=Susan J.|last4=Davidson|first4=Karina W.|last5=Epling|first5=John W.|last6=García|first6=Francisco A. R.|last7=Gillman|first7=Matthew W.|last8=Kemper|first8=Alex R.|last9=Krist|first9=Alex H.|last10=Kurth|first10=Ann E.|last11=Landefeld|first11=C. Seth|last12=Lefevre|first12=Michael|last13=Mangione|first13=Carol M.|last14=Owens|first14=Douglas K.|last15=Phillips|first15=William R.|last16=Phipps|first16=Maureen G.|last17=Pignone|first17=Michael P.|last18=Siu|first18=Albert L.|last19=Siu|first19=A. L.}} 3. ^{{cite journal|last1=Chou|first1=R|last2=Dana|first2=T|last3=Blazina|first3=I|last4=Daeges|first4=M|last5=Bougatsos|first5=C|last6=Jeanne|first6=TL|title=Screening for Dyslipidemia in Younger Adults: A Systematic Review for the U.S. Preventive Services Task Force.|journal=Annals of Internal Medicine|date=18 October 2016|volume=165|issue=8|pages=560–564|pmid=27538032|doi=10.7326/m16-0946}} |DiseasesDB = 33452 | |ICD10 = {{ICD10|E|78||e|70}} | |ICD9 = {{ICD9|272}} | |ICDO = | |OMIM = | |MedlinePlus = | |eMedicineSubj = | |eMedicineTopic = | |MeshID = D050171 | }}{{Lipid metabolism disorders}}脂質異常症 1 : Lipid disorders |
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