“Acylcarnitine hydrolase”的意思、由来-开放百科全书

词条

Acylcarnitine hydrolase

释义

References

{{redirect|HACH|the agency formerly known as the Housing Authority of the City of Houston (HACH)|Houston Housing Authority}}{{enzyme
| Name = acylcarnitine hydrolase
| EC_number = 3.1.1.28
| CAS_number = 37278-42-5
| IUBMB_EC_number = 3/1/1/28
| GO_code = 0047619
| image =
| width =
| caption =
}}

In enzymology, an acylcarnitine hydrolase ({{EC number|3.1.1.28}}) is an enzyme that catalyzes the chemical reaction

O-acylcarnitine + H₂O a fatty acid + L-carnitine

Thus, the two substrates of this enzyme are O-acylcarnitine and H₂O, whereas its two products are fatty acid and L-carnitine.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is O-acylcarnitine acylhydrolase. Other names in common use include high activity acylcarnitine hydrolase, HACH, carnitine ester hydrolase, palmitoylcarnitine hydrolase, palmitoyl-L-carnitine hydrolase, long-chain acyl-L-carnitine hydrolase, and palmitoyl carnitine hydrolase.

References

{{cite journal | vauthors = Mahadevan S, Sauer F | date = 1969 | title = Carnitine ester hydrolase of rat liver | journal = J. Biol. Chem. | volume = 244 | pages = 4448–53 | pmid = 5806585 | issue = 16 }}
{{cite journal | vauthors = Mentlein R, Reuter G, Heymann E | date = 1985 | title = Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function | journal = Arch. Biochem. Biophys. | volume = 240 | pages = 801–10 | pmid = 4026306 | doi = 10.1016/0003-9861(85)90089-X | issue = 2 }}

2 : EC 3.1.1|Enzymes of unknown structure

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