请输入您要查询的百科知识:

 

词条 Centromere protein E
释义

  1. References

  2. Further reading

{{Infobox_gene}}Centromere-associated protein E is a protein that in humans is encoded by the CENPE gene.[1][2]Centromere-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centromere-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.[2]

References

1. ^{{cite journal | vauthors = Testa JR, Zhou JY, Bell DW, Yen TJ | title = Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41, respectively, by fluorescence in situ hybridization | journal = Genomics | volume = 23 | issue = 3 | pages = 691–3 |date=Mar 1995 | pmid = 7851898 | pmc = | doi = 10.1006/geno.1994.1558 }}
2. ^{{cite web | title = Entrez Gene: CENPE centromere protein E, 312kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1062| accessdate = }}

Further reading

{{refbegin | 2}}
  • {{cite journal | author=Yen TJ |title=CENP-E is a putative kinetochore motor that accumulates just before mitosis |journal=Nature |volume=359 |issue= 6395 |pages= 536–9 |year= 1992 |pmid= 1406971 |doi= 10.1038/359536a0 |name-list-format=vanc| author2=Li G | author3=Schaar BT | display-authors=3 | last4=Szilak | first4=Illya | last5=Cleveland | first5=Don W. }}
  • {{cite journal | author=Yen TJ |title=CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase |journal=EMBO J. |volume=10 |issue= 5 |pages= 1245–54 |year= 1991 |pmid= 2022189 |doi= 10.1002/j.1460-2075.1991.tb08066.x| pmc=452779 |name-list-format=vanc| author2=Compton DA | author3=Wise D | display-authors=3 | last4=Zinkowski | first4=RP | last5=Brinkley | first5=BR | last6=Earnshaw | first6=WC | last7=Cleveland | first7=DW }}
  • {{cite journal | author=Thrower DA |title=Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor |journal=EMBO J. |volume=14 |issue= 5 |pages= 918–26 |year= 1995 |pmid= 7889940 |doi= 10.1002/j.1460-2075.1995.tb07073.x| pmc=398164 |name-list-format=vanc| author2=Jordan MA | author3=Schaar BT | display-authors=3 | last4=Yen | first4=TJ | last5=Wilson | first5=L }}
  • {{cite journal | vauthors=Wood KW, Sakowicz R, Goldstein LS, Cleveland DW |title=CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment |journal=Cell |volume=91 |issue= 3 |pages= 357–66 |year= 1997 |pmid= 9363944 |doi=10.1016/S0092-8674(00)80419-5 }}
  • {{cite journal | vauthors=Cooke CA, Schaar B, Yen TJ, Earnshaw WC |title=Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase |journal=Chromosoma |volume=106 |issue= 7 |pages= 446–55 |year= 1998 |pmid= 9391217 |doi=10.1007/s004120050266 }}
  • {{cite journal | author=Zecevic M |title=Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E |journal=J. Cell Biol. |volume=142 |issue= 6 |pages= 1547–58 |year= 1998 |pmid= 9744883 |doi=10.1083/jcb.142.6.1547 | pmc=2141767 |name-list-format=vanc| author2=Catling AD | author3=Eblen ST | display-authors=3 | last4=Renzi | first4=L | last5=Hittle | first5=JC | last6=Yen | first6=TJ | last7=Gorbsky | first7=GJ | last8=Weber | first8=MJ }}
  • {{cite journal | vauthors=Chan GK, Schaar BT, Yen TJ |title=Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1 |journal=J. Cell Biol. |volume=143 |issue= 1 |pages= 49–63 |year= 1998 |pmid= 9763420 |doi=10.1083/jcb.143.1.49 | pmc=2132809 }}
  • {{cite journal | author=Chan GK |title=Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC |journal=J. Cell Biol. |volume=146 |issue= 5 |pages= 941–54 |year= 1999 |pmid= 10477750 |doi=10.1083/jcb.146.5.941 | pmc=2169490 |name-list-format=vanc| author2=Jablonski SA | author3=Sudakin V | display-authors=3 | last4=Hittle | first4=JC | last5=Yen | first5=TJ }}
  • {{cite journal | author=Ashar HR |title=Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules |journal=J. Biol. Chem. |volume=275 |issue= 39 |pages= 30451–7 |year= 2000 |pmid= 10852915 |doi= 10.1074/jbc.M003469200 |name-list-format=vanc| author2=James L | author3=Gray K | display-authors=3 | last4=Carr | first4=D | last5=Black | first5=S | last6=Armstrong | first6=L | last7=Bishop | first7=WR | last8=Kirschmeier | first8=P }}
  • {{cite journal | author=Uren AG |title=Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype |journal=Curr. Biol. |volume=10 |issue= 21 |pages= 1319–28 |year= 2001 |pmid= 11084331 |doi=10.1016/S0960-9822(00)00769-7 |name-list-format=vanc| author2=Wong L | author3=Pakusch M | display-authors=3 | last4=Fowler | first4=Kerry J. | last5=Burrows | first5=Francis J. | last6=Vaux | first6=David L. | last7=Choo | first7=K.H.Andy }}
  • {{cite journal | author=Suzuki Y |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.gr-1640r| pmc=311086 |name-list-format=vanc| author2=Tsunoda T | author3=Sese J | display-authors=3 | last4=Taira | first4=H | last5=Mizushima-Sugano | first5=J | last6=Hata | first6=H | last7=Ota | first7=T | last8=Isogai | first8=T | last9=Tanaka | first9=T }}
  • {{cite journal | author=Liu ST |title=Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores |journal=Mol. Biol. Cell |volume=14 |issue= 4 |pages= 1638–51 |year= 2003 |pmid= 12686615 |doi= 10.1091/mbc.02-05-0074 | pmc=153128 |name-list-format=vanc| author2=Chan GK | author3=Hittle JC | display-authors=3 | last4=Fujii | first4=G | last5=Lees | first5=E | last6=Yen | first6=TJ }}
  • {{cite journal | author=Brandenberger R |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 |name-list-format=vanc| author2=Wei H | author3=Zhang S | display-authors=3 | last4=Lei | first4=Shirley | last5=Murage | first5=Jaji | last6=Fisk | first6=Gregory J | last7=Li | first7=Yan | last8=Xu | first8=Chunhui | last9=Fang | first9=Rixun }}
  • {{cite journal | vauthors=Garcia-Saez I, Blot D, Kahn R, Kozielski F |title=Crystallization and preliminary crystallographic analysis of the motor domain of human kinetochore-associated protein CENP-E using an automated crystallization procedure |journal=Acta Crystallogr. D |volume=60 |issue= Pt 6 |pages= 1158–60 |year= 2005 |pmid= 15159587 |doi= 10.1107/S0907444904009564 }}
  • {{cite journal | author=Tanudji M |title=Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay |journal=Mol. Biol. Cell |volume=15 |issue= 8 |pages= 3771–81 |year= 2005 |pmid= 15181147 |doi= 10.1091/mbc.E03-07-0482 | pmc=491836 |name-list-format=vanc| author2=Shoemaker J | author3=L'Italien L | display-authors=3 | last4=Russell | first4=L | last5=Chin | first5=G | last6=Schebye | first6=XM }}
  • {{cite journal | vauthors=Garcia-Saez I, Yen T, Wade RH, Kozielski F |title=Crystal structure of the motor domain of the human kinetochore protein CENP-E |journal=J. Mol. Biol. |volume=340 |issue= 5 |pages= 1107–16 |year= 2004 |pmid= 15236970 |doi= 10.1016/j.jmb.2004.05.053 }}
  • {{cite journal | author=Kurasawa Y |title=Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation |journal=EMBO J. |volume=23 |issue= 16 |pages= 3237–48 |year= 2005 |pmid= 15297875 |doi= 10.1038/sj.emboj.7600347 | pmc=514520 |name-list-format=vanc| author2=Earnshaw WC | author3=Mochizuki Y | display-authors=3 | last4=Dohmae | first4=Naoshi | last5=Todokoro | first5=Kazuo }}
  • {{cite journal | vauthors=Mao Y, Desai A, Cleveland DW |title=Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling |journal=J. Cell Biol. |volume=170 |issue= 6 |pages= 873–80 |year= 2005 |pmid= 16144904 |doi= 10.1083/jcb.200505040 | pmc=2171436 }}
  • {{cite journal | author=Nousiainen M |title=Phosphoproteome analysis of the human mitotic spindle |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 | pmc=1459365 |name-list-format=vanc| author2=Silljé HH | author3=Sauer G | display-authors=3 | last4=Nigg | first4=EA | last5=Körner | first5=R }}
{{refend}}{{PDB Gallery|geneid=1062}}{{Chromosome genetics}}{{gene-4-stub}}
随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/9/20 10:54:11