| 释义 |
- References
- External links
- Further reading
{{Infobox_gene}}Cirhin is a protein that in humans is encoded by the CIRH1A gene.[1][2][3] It has been associated with North American Indian childhood cirrhosis (not to be confused with Indian Childhood Cirrhosis which has greatly decreased over the past 100 years and was thought to be secondary to the use of various herbal remedies), a form of cirrhosis of the liver occurring in American Indian children from the Abitibi region of northern Quebec.[4]References1. ^{{cite journal | vauthors = Betard C, Rasquin-Weber A, Brewer C, Drouin E, Clark S, Verner A, Darmond-Zwaig C, Fortin J, Mercier J, Chagnon P, Fujiwara TM, Morgan K, Richter A, Hudson TJ, Mitchell GA | title = Localization of a recessive gene for North American Indian childhood cirrhosis to chromosome region 16q22-and identification of a shared haplotype | journal = Am J Hum Genet | volume = 67 | issue = 1 | pages = 222–8 |date=Aug 2000 | pmid = 10820129 | pmc = 1287080 | doi = 10.1086/302993 }}
2. ^{{cite journal | vauthors = Chagnon P, Michaud J, Mitchell G, Mercier J, Marion JF, Drouin E, Rasquin-Weber A, Hudson TJ, Richter A | title = A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis | journal = Am J Hum Genet | volume = 71 | issue = 6 | pages = 1443–9 |date=Nov 2002 | pmid = 12417987 | pmc = 378590 | doi = 10.1086/344580 }}
3. ^{{cite web | title = Entrez Gene: CIRH1A cirrhosis, autosomal recessive 1A (cirhin)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84916| accessdate = }}
4. ^{{cite journal |vauthors=Chagnon P, Michaud J, Mitchell G |title=A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis |journal=Am. J. Hum. Genet. |volume=71 |issue=6 |pages=1443–9 |year=2002 |pmid=12417987 |doi=10.1086/344580 |url=http://www.ajhg.org/AJHG/fulltext/S0002-9297(07)60865-9 |pmc=378590|display-authors=etal}}
External links- {{UCSC gene info|CIRH1A}}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=López-Fernández LA, del Mazo J |title=Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. |journal=Mamm. Genome |volume=7 |issue= 9 |pages= 698–700 |year= 1996 |pmid= 8703127 |doi=10.1007/s003359900210 }}
- {{cite journal | vauthors=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |journal=DNA Res. |volume=8 |issue= 6 |pages= 319–27 |year= 2002 |pmid= 11853319 |doi=10.1093/dnares/8.6.319 }}
- {{cite journal | vauthors=Scherl A, Couté Y, Déon C |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Andersen JS, Lam YW, Leung AK |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 |display-authors=etal}}
- {{cite journal | vauthors=Yu B, Mitchell GA, Richter A |title=Nucleolar localization of cirhin, the protein mutated in North American Indian childhood cirrhosis. |journal=Exp. Cell Res. |volume=311 |issue= 2 |pages= 218–28 |year= 2006 |pmid= 16225863 |doi= 10.1016/j.yexcr.2005.08.012 }}
{{refend}}{{gene-16-stub}} |