Latta House may refer to:

• May-Latta House, Prestonsburg, Kentucky, listed on the National Register of Historic Places (NRHP) in Floyd County
• E. D. Latta Nurses' Residence, Asheville, North Carolina, listed on the NRHP in Buncombe County
• Latta House (Huntersville, North Carolina), listed on the NRHP in Mecklenburg County
• Rev. M.L. Latta House, Raleigh, North Carolina, NRHP-listed
• Latta House (Dyersburg, Tennessee), NRHP-listed

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