词条 | Alentemol |
释义 |
| Name = | ImageFile = alentemol.svg | ImageSize = 150px | IUPACName = 2-(Dipropylamino)-2,3-dihydro-1H-phenalen-5-ol | OtherNames = |Section1={{Chembox Identifiers | Abbreviations = | CASNo = 112891-97-1 | EINECS = | PubChem = 60574 | ChemSpiderID = 54603 | SMILES = CCCN(CCC)C1CC2=CC=CC3=CC(=CC(=C23)C1)O | InChI = 1/C19H25NO/c1-3-8-20(9-4-2)17-10-14-6-5-7-15-12-18(21)13-16(11-17)19(14)15/h5-7,12-13,17,21H,3-4,8-11H2,1-2H3 | InChIKey = TWUJBHBRYYTEDL-UHFFFAOYAC | StdInChI = 1S/C19H25NO/c1-3-8-20(9-4-2)17-10-14-6-5-7-15-12-18(21)13-16(11-17)19(14)15/h5-7,12-13,17,21H,3-4,8-11H2,1-2H3 | StdInChIKey = TWUJBHBRYYTEDL-UHFFFAOYSA-N | RTECS = | MeSHName = | ChEBI = | ChEMBL = 2104081 | KEGG = }} |Section2={{Chembox Properties | C=19 | H=25 | N=1 | O=1 | Appearance = | Density = | MeltingPt = | MeltingPt_notes = | BoilingPt = | BoilingPt_notes = | Solubility = | SolubleOther = | Solvent = | LogP = | VaporPressure = | HenryConstant = | AtmosphericOHRateConstant = | pKa = | pKb = |Section3={{Chembox Structure | CrystalStruct = | Coordination = | MolShape = |Section4={{Chembox Thermochemistry | DeltaHf = | DeltaHc = | Entropy = | HeatCapacity = |Section5={{Chembox Pharmacology | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = |Section6={{Chembox Explosive | ShockSens = | FrictionSens = | DetonationV = | REFactor = |Section7={{Chembox Hazards | ExternalSDS = | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = | SPhrases = | RSPhrases = | FlashPt = | AutoignitionPt = | ExploLimits = | LD50 = | PEL = |Section8={{Chembox Related | OtherAnions = | OtherCations = | OtherFunction = | OtherFunction_label = | OtherCompounds = }}Alentemol (INN) (developmental code name U-66444B), or alentamol, is a selective dopamine autoreceptor agonist described as an antipsychotic, which was never marketed.[1][2] References1. ^{{cite book|author=William Andrew Publishing|title=Pharmaceutical Manufacturing Encyclopedia, 3rd Edition|url=https://books.google.com/books?id=_J2ti4EkYpkC&pg=PA143|date=22 October 2013|publisher=Elsevier|isbn=978-0-8155-1856-3|pages=143–}} {{Antipsychotics}}{{Dopaminergics}}{{nervous-system-drug-stub}}2. ^{{cite book|author=A.F. Casy|title=The Steric Factor in Medicinal Chemistry: Dissymmetric Probes of Pharmacological Receptors|url=https://books.google.com/books?id=-mQFCAAAQBAJ&pg=PA178|date=11 November 2013|publisher=Springer Science & Business Media|isbn=978-1-4899-2397-4|pages=178–}} 3 : Antipsychotics|Dopamine agonists|Abandoned drugs |
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