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词条 Astrid Linthorst
释义

  1. Career

     Education  Research focus/interests  Awards  Positions of trust and research assessments 

  2. Publications

  3. References

  4. External links

{{Infobox scientist
| name = Astrid Linthorst
| fields = Neuroscience
| workplaces = University of Bristol, School of Clinical Sciences
| education = PhD Rudolf Magnus Institute, University of Utrecht
| known_for = Neuroendocrine and behavioral responses to stress
| awards = Wellcome Trust Grant, BBSRC Grant
}}Astrid Linthorst is a professor of neuroscience at the School of Clinical Sciences at the University of Bristol, UK. Specializing in the neurochemistry and neuroendocrinology of stress and behavior, she heads a research group on the mechanisms that support coping with stress in the brain.[1] She is also chair of the Scientific Programme Committee of the ECNP Congress and a member of the European College of Neuropsychopharmacology (ECNP) Executive Committee.[2]

Career

Education

Linthorst received her PhD in Pharmacology at the Rudolf Magnus Institute of Neuroscience at the University of Utrecht, the Netherlands. After completing her PhD, she was a scientist and research group head at the Max Planck Institute in Munich. She is currently a professor of neuroscience at the University of Bristol. Prior to this appointment, she served as a senior lecturer and reader in neuroscience within the department. She is also the director of the MSc program in molecular neuroscience and co-director of the MRes program in systems neuroscience.[3]

Research focus/interests

Linthorst heads a research group that studies stress, specifically the neurochemical and neuroendocrine mechanisms that support coping with stress. The group also studies the effects of exercise on stress relief. The research group is funded by the Wellcome Trust and the European Union.[1]

Awards

Linthorst has been awarded two grants from the Wellcome Trust, a biomedical research charity based in London. She also received a grant from the Biotechnology and Biological Sciences Research Council (BBSRC).[3]

Positions of trust and research assessments

Linthorst is a member of the Society for Neuroscience, the British Neuroscience Association, the British Society for Neuroendocrinology, the British Association for Psychopharmacology, and the European College of Neuropsychopharmacology (ECNP), where she chairs the Scientific Programme Committee of the ECNP Congres.[3]

Publications

Linthorst has published extensively.[4]

Key publications include:

  • {{cite journal |last= Beekman |first= Marjolein

|last2= Flachskamm |first2= Cornelia |last3= Linthorst |first3= Astrid C. E. |date= May 2005 |title= Effects of exposure to a predator on behaviour and serotonergic neurotransmission in different brain regions of C57bl/6N mice |journal= European Journal of Neuroscience |volume= 21|issue= 10|pages= 2825–2836 |doi= 10.1111/j.1460-9568.2005.04107.x}}
  • {{cite journal |last= De Groote

|first= Lotte |last2= Peñalva |first2= Rosana G. |last3= Flachskamm | first3= Cornelia |last4= Reul | first4= Johannes M. H. M. |last5= Linthorst |first5= Astrid C. E. |date=July 2005 |title= Differential monoaminergic, neuroendocrine and behavioural responses after central administration of corticotropin-releasing factor receptor type 1 and type 2 agonists |journal= Journal of Neurochemistry |volume= 94|issue= 1|pages= 45–56 |doi= 10.1111/j.1471-4159.2005.03164.x |pmid=15953348}}
  • {{cite journal |last= Droste |first= Susanne K. |last2= Gesing |first2= Angela |last3= Ulbricht |first3= Sabine |last4= Müller |first4= Marianne B. |last5= Linthorst |first5= Astrid C. E. |last6= Reul |first6= Johannes M. H. M. |date= July 2003 |title= Effects of long-term voluntary exercise on the hypothalamic-pituitary-adrenal axis in mice |url= http://press.endocrine.org/doi/pdf/10.1210/en.2003-0097 |journal= Endocrinology |publisher=The Endocrine Society |volume= 144|issue= 7|pages= 3012–3023|doi=10.1210/en.2003-0097 |access-date=4 November 2015}}
  • {{cite journal |last= Peñalva |first= Rosana G. |last2= Lancel |first2= Marike |last3= Flachskamm |first3= Cornelia |last4= Reul |first4= Johannes M. H. M. |last5= Holsboer |first5= Florian |last6= Linthorst | first6= Astrid C. E. |date= May 2003 |title= Effect of sleep and sleep deprivation on serotonergic neurotransmission in the hippocampus: a combined in vivo microdialysis/EEG study in rats |journal= European Journal of Neuroscience |publisher= Federation of European Neuroscience Societies |volume= 17|issue= 9|pages= 1896–1906|doi= 10.1046/j.1460-9568.2003.02612.x}}
  • {{cite journal |last= Linthorst |first= Astrid C.E.|last2= Peñalva |first2= Rosana G. |last3= Flachskamm |first3= Cornelia |last4= Holsboer |first4= Florian |last5= Reul |first5= Johannes M. H. M. |date= December 2002|title= Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropinreleasing hormone receptor-dependent mechanism |journal= European Journal of Neuroscience

|publisher= Federation of European Neuroscience Societies |volume= 16|issue= 12|pages= 2441–2452|doi= 10.1046/j.1460-9568.2002.02400.x }}
  • {{cite journal |last= Linthorst |first= Astrid C. E. |last2= Flachskamm |first2= Cornelia |last3= Barden |first3= Nicholas |last4= Holsboer |first4= Florian |last5= Reul|first5= Johannes M. H. M. |date= January 2000|title= Glucocorticoid receptor impairment alters CNS responses to a psychological stressor: an in vivo microdialysis study in transgenic mice |journal= European Journal of Neuroscience |volume= 12 |issue= 1 |pages= 283–291|doi= 10.1046/j.1460-9568.2000.00878.x }}
  • {{cite journal |last= Linthorst |first= Astrid C. E. |last2= Karanth

|first2= Sharada |last3= Barden |first3= Nicholas |last4= Florian |first4= Holsboer |last5= Reul |first5= Johannes M. H. M. |date= January 1999 |title= Impaired glucocorticoid receptor function evolves in aberrant physiological responses to bacterial endotoxin |journal= European Journal of Neuroscience |volume= 11|issue= 1|pages= 178–186|doi= 10.1046/j.1460-9568.1999.00425.x }}
  • {{cite journal |last= Linthorst |first= Astrid C. E. |last2= Cornelia |first2= Flachskamm |last3= Hopkins |first3= Stephen J. |last4= Hoadley |first4= Margaret E. |last5= Labeur

|first5= Marta S. |last6= Holsboer |first6= Florian|last7= Reul |first7= Johannes M. H. M.
|date=1 June 1997 |title= Long-term intracerebroventricular infusion of corticotropin-releasing hormone alters neuroendocrine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge |url= http://www.jneurosci.org/content/17/11/4448.full.pdf+html |journal= The Journal of Neuroscience |volume= 17|issue= 11 |pages= 4448–4460|access-date=4 November 2015}}
  • {{cite journal |last= Linthorst |first= Astrid C. E.|last2= Flachskamm |first2= Cornelia |last3= Müller-Preuss |first3= Peter |last4= Holsboer |first4= Florian |last5= Reul |first5= Johannes M. H. M. |date= April 1995|title= Effect of bacterial endotoxin and interleukin-1ß on hippocampal serotonergic neurotransmission, behavioral activity and free corticosterone levels: an in vivo microdialysis study |url= http://www.jneurosci.org/content/15/4/2920.long |journal= The Journal of Neuroscience |volume= 15|issue= 4|pages= 2920–2934|access-date=4 November 2015}}
  • {{cite journal |last= Linthorst |first= Astrid C. E.|last2= Flachskamm |first2= Cornelia |last3= Holsboer |first3= Florian |last4= Reul |first4= Johannes M. H. M. |date= August 1994|title= Local administration of recombinant human interleukin-1ß in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature |journal= Endocrinology |volume=135 |issue=2 |pages= 520–532 |doi= 10.1210/endo.135.2.7518383 }}

References

1. ^{{cite web |url= http://www.bristol.ac.uk/clinical-sciences/people/astrid-c-linthorst/index.html |title= Professor Astrid Linthorst | author= |website=bristol.ac.uk | access-date=4 November 2015}}
2. ^{{cite web|url=http://www.ecnp.eu/about-ecnp/who-we-are/executive-committee.aspx |title=The Executive Committee |website=ecnp.eu |access-date=4 November 2015 |deadurl=yes |archiveurl=https://web.archive.org/web/20150706133535/http://www.ecnp.eu/about-ecnp/who-we-are/executive-committee.aspx |archivedate=6 July 2015 }}
3. ^{{cite web|url=https://www.ecnp.eu/~/media/Files/ecnp/Projects%20and%20initiatives/Certificate/CV%20Fellow%20members/2013-04-04%20Astrid%20Linthorst%20short%20CV%20for%20ECNP%20Fellow.pdf |title=CV Astrid Linthorst |author= |date=4 April 2013 |website=ecnp.eu |access-date=4 November 2015 |deadurl=yes |archiveurl=https://web.archive.org/web/20160305023719/https://www.ecnp.eu/~/media/Files/ecnp/Projects%20and%20initiatives/Certificate/CV%20Fellow%20members/2013-04-04%20Astrid%20Linthorst%20short%20CV%20for%20ECNP%20Fellow.pdf |archivedate=5 March 2016 |df=dmy }}
4. ^{{cite web |url= http://research-information.bristol.ac.uk/en/persons/astrid-c-e-linthorst(b5757ab5-5f3a-4e5c-a089-423b19bb0e80)/publications.html |title= Astrid CE Lintohorst – Research Outputs |author= |website= bristol.ac.uk | access-date=4 November 2015}}

External links

  • “European College of Neuropsychopharmacology (ECNP)”
  • “Bristol University”
  • “Wellcome Trust”
  • “Biotechnology and Biological Sciences Research Council”
{{Authority control}}{{Use dmy dates|date=August 2016}}{{DEFAULTSORT:Linthorst, Astrid}}

5 : Living people|Year of birth missing (living people)|Women neuroscientists|Academics of the University of Bristol|Utrecht University alumni

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