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词条 Methyl-n-amylnitrosamine
释义

  1. References

{{DISPLAYTITLE:Methyl-n-amylnitrosamine}}{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 425012515
| Name = Methyl-n-amylnitrosamine
| ImageFile = Methylamylnitrosamine.png
| ImageFile_Ref = {{chemboximage|correct|??}}
| ImageSize = 160
| ImageName = Skeletal formula of methyl-n-amylnitrosamine
| PIN = N-Methyl-N-pentylnitrous amide
|Section1={{Chembox Identifiers
| CASNo = 13256-07-0
| CASNo_Ref = {{cascite|correct|??}}
| PubChem = 25805
| ChemSpiderID = 24041
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| MeSHName = N-amyl-N-methylnitrosamine
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 140674
| ChEMBL = 352469
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| SMILES = CCCCCN(C)N=O
| StdInChI = 1S/C6H14N2O/c1-3-4-5-6-8(2)7-9/h3-6H2,1-2H3
| StdInChI_Ref = {{chemspidercite|correct|chemspider}}
| StdInChIKey = KSFCDINBDBFFSI-UHFFFAOYSA-N
| StdInChIKey_Ref = {{chemspidercite|correct|chemspider}}
}}
|Section2={{Chembox Properties
| C=6 | N=2 | H=14 | O=1
| Appearance = Yellow, transparent liquid
| LogP = 1.542
}}
|Section3={{Chembox Related
| OtherFunction_label = amines
| OtherFunction = {{unbulleted list|Dipropylamine|Norspermidine|Spermidine}}
| OtherCompounds = Agmatine
}}
}}

Methyl-n-amylnitrosamine (MNAN) is a potential carcinogen[1] It is metabolized in the liver by the enzyme CYP2A6.

References

1. ^{{cite journal |vauthors=Bulay O, Mirvish SS |title=Carcinogenesis in rat esophagus by intraperitoneal injection of different doses of methyl-n-amylnitrosamine |journal=Cancer Res. |volume=39 |issue=9 |pages=3644–6 |date=September 1979 |pmid=476689 |doi= |url=http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=476689}}
{{organic-compound-stub}}

2 : Carcinogens|Nitrosamines

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