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词条 Denise Darvall
释义

  1. Injuries

  2. Father gives permission

  3. Declaration of death

  4. Organ donation

  5. See also

  6. References

  7. Bibliography

  8. External links

{{more citations needed|date=August 2017}}{{use dmy dates|date=November 2012}}{{use South African English|date=November 2012}} __NOTOC__

Denise Ann Darvall (27 February 1942{{spaced ndash}}3 December 1967)[1] was the donor in the world's first successful human heart transplant, performed at Groote Schuur Hospital, South Africa, by a team of surgeons led by Christiaan Barnard.

Injuries

Darvall was seriously injured in a car accident on Main Road in Observatory, Cape Town. She and her family were visiting friends for afternoon tea and went shopping for cake. She and her mother were run over by a driver who failed to see them. This was due to a large truck that obscured his view of them, and their view of his car. Her mother died immediately. Darvall sustained a skull fracture and severe head injuries after the car flung her across the road; her head hit the wheel cap of her car. She required life support to remain alive, and was essentially brain dead. At 9 p.m. on the day of the accident, the resuscitation team stopped attempts to revive her.

Father gives permission

Edward Darvall arranged for his fourteen-year son, who had witnessed the accident, to be taken away from the hospital. The 66-year-old Edward was also given a sedative, and he waited while doctors attempted to save his daughter. Two doctors, Coert Venter and Bertie Bosman, informed him that there was nothing further they could do for Denise. Bosman explained that there was a man in the hospital they might be able to help, and asked Edward if he would consider allowing them to transplant Denise's heart.[2]

Edward Darwal later said that, after thinking about his daughter for four minutes, he reached his decision and gave permission.[2]

The public record shows that Edward Darvall mostly shunned publicity. He had undergone major stomach surgery, but his strength of character and dignity earned him many admirers. Before the joint funeral of his wife and daughter, he asked for donations to be sent to the Groote Schuur cardiac unit.

Darvall was present at the trial of the drunk driver who was convicted of murder. Darvall, heartbroken, made a statement through a lawyer, asking the magistrate to show the “greatest possible mercy” to the driver. "The tragic death of his daughter was not meaningless, but benefited humanity," he said.[3]

Declaration of death

Surgeons had a serious ethical problem because death then could only be declared by whole-body standards. The Harvard Criteria of Brain Death was not developed until 1968, nor was it adopted in South Africa or elsewhere for some years. The problem in this case was that, although Denise's brain was damaged, her heart was healthy. Various reports over the years attributed conflicting reasons for her heart stopping. For 40 years, Barnard's brother Marius kept a secret: rather than wait for her heart to stop beating, at Marius's urging, Christiaan had injected potassium into Denise's heart to paralyze it. This rendered her technically dead by the whole-body standard.[4]

Organ donation

After her father gave his consent, Darvall's heart was donated to Louis Washkansky. Her kidneys were given to 10-year-old Jonathan van Wyk. Due to apartheid, the kidney donation to Van Wyk was controversial[5] because he was khoi, while Denise was white. Washkansky lived 18 days before succumbing to pneumonia.

See also

  • Christiaan Barnard
  • Hamilton Naki
  • Heart transplantation

References

1. ^ancestry42 {{webarchive|url=https://archive.is/20130117004633/http://ancestry24.com/?group=on&s=search&ref=recent&srchName=&srchSurname=darvall |date=17 January 2013 }}
2. ^[https://books.google.com/books?id=nBYTCwAAQBAJ&pg=PA189&dq=%22Bosman+and+Venter+withdrew,+stressing+that+he+should+take+as+long+as+he+needed+to+consider+their+request.+They+would+understand+if+he+declined+to+give+his+consent.%22&hl=en&sa=X&ved=0ahUKEwj6j-6f3srVAhVGx1QKHb4qBbYQ6AEIJjAA#v=onepage&q=%22Bosman%20and%20Venter%20withdrew%2C%20stressing%20that%20he%20should%20take%20as%20long%20as%20he%20needed%20to%20consider%20their%20request.%20They%20would%20understand%20if%20he%20declined%20to%20give%20his%20consent.%22&f=false Every Second Counts: The Race to Transplant the First Human Heart], Donald McRae, New York: Putnam, 2006, page 189.
3. ^{{Cite web|url=https://transplantaciya.com/peresadka-serdca/|title=Heart transplant|last=|first=|date=|website=transplantaciya.com|language=ru-RU|archive-url=|archive-date=|dead-url=|access-date=2018-11-23}}
4. ^Every Second Counts, McRae, page 192.
5. ^{{cite web|last1=Malan|first1=M|title=Darvall, Denise|url=http://www.sahistory.org.za/people/denise-darvall|website=sahistory.org|publisher=South Africa History|accessdate=30 May 2015}}

Bibliography

  • Christiaan Barnard and Curtiss Bill Pepper, "One Life," MacMillan, New York, 1969.
  • Christiaan Barnard, "The Second Life," Vlaeberg Publishers, South Africa, 1993.

External links

  • South African history: Denise Darvall
  • [https://web.archive.org/web/20050313185148/http://www.gsh.co.za/ab/heart.html Groote Schuur Hospital account of Washkansky’s heart transplant]
{{DEFAULTSORT:Darvall, Denise}}

5 : 1942 births|1967 deaths|Organ transplant donors|Road incident deaths in South Africa|South African people

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