词条 | Dihydroquinidine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 343510953 | ImageFile = Dihydroquinidine structure.svg | ImageSize = 200 | IUPACName = (S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol | OtherNames = (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol | Section1 = {{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 1435-55-8 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 280522 | PubChem = 91503 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 8P68XPY4HG | SMILES = | Section2 = {{Chembox Properties | Formula = C20H26N2O2 | MolarMass = 326.4 g/mol | Appearance = | Density = | MeltingPtC = 169 to 172 | MeltingPt_notes = | BoilingPt = | Solubility = | Section6 = {{Chembox Pharmacology | ATCCode_prefix = C01 | ATCCode_suffix = BA13 | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Dihydroquinidine (also called hydroquinidine) is an organic compound, a cinchona alkaloid closely related to quinine. The specific rotation is +226° in ethanol at 2g/100 ml. A derivative of this molecule is used as chiral ligand in the AD-mix for Sharpless dihydroxylation. The substance is also a class Ia antiarrhythmic medication.[1] See also
References1. ^Drugs.com: {{Drugs.com|international|hydroquinidine}} for hydroquinidine. {{Antiarrhythmic agents}} 5 : Alcohols|Alkaloids|Phenol ethers|Quinolines|Quinuclidines |
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