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词条 Dihydroquinidine
释义

  1. See also

  2. References

{{Refimprove|date=October 2008}}{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 343510953
| ImageFile = Dihydroquinidine structure.svg
| ImageSize = 200
| IUPACName = (S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
| OtherNames = (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
| Section1 = {{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 1435-55-8
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 280522
| PubChem = 91503
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 8P68XPY4HG
| SMILES =
| Section2 = {{Chembox Properties
| Formula = C20H26N2O2
| MolarMass = 326.4 g/mol
| Appearance =
| Density =
| MeltingPtC = 169 to 172
| MeltingPt_notes =
| BoilingPt =
| Solubility =
| Section6 = {{Chembox Pharmacology
| ATCCode_prefix = C01
| ATCCode_suffix = BA13
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}

Dihydroquinidine (also called hydroquinidine) is an organic compound, a cinchona alkaloid closely related to quinine. The specific rotation is +226° in ethanol at 2g/100 ml. A derivative of this molecule is used as chiral ligand in the AD-mix for Sharpless dihydroxylation.

The substance is also a class Ia antiarrhythmic medication.[1]

See also

  • Dihydroquinine

References

1. ^Drugs.com: {{Drugs.com|international|hydroquinidine}} for hydroquinidine.
{{Antiarrhythmic agents}}

5 : Alcohols|Alkaloids|Phenol ethers|Quinolines|Quinuclidines

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