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词条 Troxacitabine
释义

  1. References

{{one source|date=August 2014}}{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 470618288
| IUPAC_name = 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one
| image = Troxacitabine.svg
| width = 200px
| tradename =
| pregnancy_category =
| legal_status =
| routes_of_administration =
| bioavailability =
| metabolism =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 145918-75-8
| ATC_suffix =
| PubChem = 151173
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 399955
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 60KQZ0388Y
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 359164
| C=8 | H=11 | N=3 | O=4
| molecular_weight = 213.19 g/mol
| smiles = O=C1/N=C(/N)\\C=C/N1[C@H]2O[C@H](OC2)CO
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RXRGZNYSEHTMHC-BQBZGAKWSA-N
| synonyms =
}}Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.[1]

References

1. ^{{Cite journal | doi = 10.1080/10428190600909578 |author1=Vose, Julie M. |author2=Panwalkar, Amit |author3=Belanger, Robert |author4=Coiffier, Bertrand |author5=Baccarani, Michele |author6=Gregory, Stephanie A. |author7=Facon, Thierry |author8=Fanin, Renato |author9=Caballero, Dolores |author10=Ben-Yehuda, Dina |author11=Giles, Francis | title = A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma | journal = Leukemia & Lymphoma | year = 2007 | volume = 48 | issue = 1 | pages = 39–45}}
{{Pharma-stub}}

1 : Experimental cancer drugs

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