词条 | Troxacitabine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470618288 | IUPAC_name = 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one | image = Troxacitabine.svg | width = 200px | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | metabolism = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 145918-75-8 | ATC_suffix = | PubChem = 151173 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 399955 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 60KQZ0388Y | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 359164 | C=8 | H=11 | N=3 | O=4 | molecular_weight = 213.19 g/mol | smiles = O=C1/N=C(/N)\\C=C/N1[C@H]2O[C@H](OC2)CO | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = RXRGZNYSEHTMHC-BQBZGAKWSA-N | synonyms = }}Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.[1] References1. ^{{Cite journal | doi = 10.1080/10428190600909578 |author1=Vose, Julie M. |author2=Panwalkar, Amit |author3=Belanger, Robert |author4=Coiffier, Bertrand |author5=Baccarani, Michele |author6=Gregory, Stephanie A. |author7=Facon, Thierry |author8=Fanin, Renato |author9=Caballero, Dolores |author10=Ben-Yehuda, Dina |author11=Giles, Francis | title = A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma | journal = Leukemia & Lymphoma | year = 2007 | volume = 48 | issue = 1 | pages = 39–45}} {{Pharma-stub}} 1 : Experimental cancer drugs |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。