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词条 Descinolone acetonide
释义

  1. References

{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
| image = Descinolone acetonide.svg
| width =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 2135-14-0
| CAS_supplemental =
| class = Corticosteroid; Glucocorticoid
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 11954034
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID = 10128329
| UNII = ENR9Z582HW
| KEGG = D03691
| ChEBI = 34672
| ChEMBL = 2106177
| C=24 | H=31 | F=1 | O=5
| SMILES = CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC(O2)(C)C
| StdInChI_Ref =
| StdInChI = 1S/C24H31FO5/c1-13(26)24-19(29-20(2,3)30-24)11-17-16-7-6-14-10-15(27)8-9-21(14,4)23(16,25)18(28)12-22(17,24)5/h8-10,16-19,28H,6-7,11-12H2,1-5H3/t16-,17-,18-,19+,21-,22-,23-,24+/m0/s1
| StdInChIKey_Ref =
| StdInChIKey = BSHYASCHOGHGHW-PIQRJGQMSA-N
| synonyms = CL-27071; Desoxytriamcinolone acetonide; 21-Desoxytriamcinoline acetonide; 9α-Fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 9α-Fluoro-11β-hydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
}}Descinolone acetonide (developmental code name CL-27071), also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA362|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=362–}}
{{Glucocorticoid receptor modulators}}{{steroid-stub}}

7 : Acetonides|Alcohols|Corticosteroid cyclic ketals|Diketones|Fluoroarenes|Glucocorticoids|Pregnanes

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