词条 | Descinolone acetonide |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one | image = Descinolone acetonide.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 2135-14-0 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 11954034 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 10128329 | UNII = ENR9Z582HW | KEGG = D03691 | ChEBI = 34672 | ChEMBL = 2106177 | C=24 | H=31 | F=1 | O=5 | SMILES = CC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC(O2)(C)C | StdInChI_Ref = | StdInChI = 1S/C24H31FO5/c1-13(26)24-19(29-20(2,3)30-24)11-17-16-7-6-14-10-15(27)8-9-21(14,4)23(16,25)18(28)12-22(17,24)5/h8-10,16-19,28H,6-7,11-12H2,1-5H3/t16-,17-,18-,19+,21-,22-,23-,24+/m0/s1 | StdInChIKey_Ref = | StdInChIKey = BSHYASCHOGHGHW-PIQRJGQMSA-N | synonyms = CL-27071; Desoxytriamcinolone acetonide; 21-Desoxytriamcinoline acetonide; 9α-Fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 9α-Fluoro-11β-hydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione }}Descinolone acetonide (developmental code name CL-27071), also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid corticosteroid which was never marketed.[1] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA362|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=362–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 7 : Acetonides|Alcohols|Corticosteroid cyclic ketals|Diketones|Fluoroarenes|Glucocorticoids|Pregnanes |
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