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词条 Chemoprotective agent
释义

  1. Risks

  2. References

  3. External links

A Chemo-protective agent[1] is a medical term that describes a drug that helps to reduce the side effects on the body while undergoing chemotherapy. These agents protects specific body parts from the harmful anti-cancer treatments that could potentially cause permanent damage to important bodily tissues. Chemo-protective agents have only recently been introduced as a factor involved with chemotherapy with the intent to assist those cancer patients that require treatment, which as an end result, improves the patients quality of life.

Examples[2][3] include:

  • Amifostine, approved by the FDA in 1995, which helps prevent kidney damage in patients undergoing cisplatin and carboplatin chemotherapy
  • Mesna, approved by the FDA in 1988, which helps prevent hemorrhagic cystitis (bladder bleeding) in patients undergoing cyclophosphamide or ifosfamide chemotherapy
  • Dexrazoxane, approved by the FDA in 1995, which helps prevent heart problems in patients undergoing doxorubicin chemotherapy

Risks

Chemo-protective agents are common drugs and like many other drugs, may have side effects of their own. Each agent has different side effects though the most common consist of dizziness, sleepiness, nausea, fever, etc.[4] It is important to discuss the side effects of these drugs with a doctor before using them to combat any type of chemotherapy to insure the drug will benefit you.   

References

1. ^{{Cite web|url=https://www.cancer.gov/publications/dictionaries/cancer-terms|title=NCI Dictionary of Cancer Terms|date=2011-02-02|website=National Cancer Institute|language=en|access-date=2019-03-14}}
2. ^{{Cite web|url=http://chemocare.com/chemotherapy/what-is-chemotherapy/chemoprotective-agents.aspx|title=Chemoprotective Agents: Amifostine, Mesna, Dexrazoxane - What is Chemotherapy? - Chemocare|last=Cancer|first=Cleveland Clinic|website=chemocare.com|access-date=2016-10-13}}
3. ^{{Cite book|title=First Aid for the USMLE Step 1 2016|last=|first=|publisher=|year=|isbn=9781259587375|location=|pages=|via=}}
4. ^{{Cite web|url=https://www.rxlist.com/ethyol-side-effects-drug-center.htm|title=Common Side Effects of Ethyol (Amifostine) Drug Center|website=RxList|language=en|access-date=2019-03-25}}

External links

  • Chemoprotective entry in the public domain NCI Dictionary of Cancer Terms
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1 : Antineoplastic drugs

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