| 词条 | Dicistroviridae | |||||||||||||||||||||||||||||||||||||||||
| 释义 |
| taxon = Dicistroviridae | subdivision_ranks = Genera | subdivision =
}}Dicistroviridae is a family of viruses in the order Picornavirales. Invertebrates, including aphids, leafhoppers, flies, bees, ants, and silkworms, serve as natural hosts. There are currently 15 species in this family, divided among 2 genera.[1][2] Diseases associated with this family include: DCV: increased reproductive potential. extremely pathogenic when injected with high associated mortality. CrPV: paralysis and death.[2][3] TaxonomyAlthough many dicistroviruses were initially placed in the Picornaviridae, they have since been reclassified into their own family. The name (Dicistro) is derived from the characteristic dicistronic arrangement of the genome. This family is a member of the Order Picornavirales (along with the families Iflaviridae, Picornaviridae, and Secoviridae and Marnaviridae). Within this order, the gene order is the gene order of the nonstructural proteins Hel(helicase)-Pro(protease)-RdRp(polymerase). The Dicistroviridae can be distinguished from the members of the taxa by the location of their structural protein genes at the 3' end rather than the 5' end (as found in Iflavirus, Picornaviridae and Secoviridae) and by having two genomic segments rather than a single one (as in the Comovirus).[2] Group: ssRNA(+)Order: PicornaviralesFamily: Dicistroviridae Genus: Aparavirus
Linepithema humile virus 1 is possibly a member of Dicistroviridae, of unclear placement. StructureViruses in Dicistroviridae are non-enveloped, with icosahedral geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 8.5-10.2kb in length. The genome has 2 open reading frames.[2][3]
Life cycleEntry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by viral initiation, and ribosomal skipping. Invertebrates serve as the natural host. Transmission routes are contamination.[2][3]
RNA structural elementsMany of the Dicistroviridae genomes contains structured RNA elements. For example, the Cripaviruses have an internal ribosome entry site,[4] which mimics a Met-tRNA and is used in the initiation of translation.[5] References1. ^{{cite journal|last1=Valles|first1=SM|last2=Chen|first2=Y|last3=Firth|first3=AE|last4=Guérin|first4=DM|last5=Hashimoto|first5=Y|last6=Herrero|first6=S|last7=de Miranda|first7=JR|last8=Ryabov|first8=E|last9=ICTV Report Consortium|title=ICTV Virus Taxonomy Profile: Dicistroviridae.|journal=The Journal of General Virology|date=March 2017|volume=98|issue=3|pages=355–356|pmid=28366189|doi=10.1099/jgv.0.000756}} 2. ^1 2 3 4 5 {{cite web|title=Dicistrovirdae|url=http://www.ictv.global/report/dicistroviridae|website=ICTV Online (10th) Report|language=en}} 3. ^1 2 {{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/36.html|publisher=ExPASy|accessdate=15 June 2015}} 4. ^{{cite journal | last = Kanamori | first = Y |author2=Nakashima N | year = 2001 | title = A tertiary structure model of the internal ribosome entry site (IRES) for methionine-independent initiation of translation | journal = RNA | volume = 7 | pages = 266–274 | pmid = 11233983 | doi = 10.1017/S1355838201001741 | issue = 2 | pmc = 1370084}} 5. ^{{cite journal | author = Malys N, McCarthy JEG | title = Translation initiation: variations in the mechanism can be anticipated |journal = Cellular and Molecular Life Sciences | volume = 68 | issue = 6 | pages = 991–1003 | year = 2010 | pmid = 21076851 | doi =10.1007/s00018-010-0588-z}}
External links
3 : Dicistroviridae|Picornavirales|Virus families |
|||||||||||||||||||||||||||||||||||||||||
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。