GDF may refer to:

• Gaz de France, a defunct French energy company
• General Data Format for Biomedical Signals
• Geographic Data Files
• Geological disposal facility
• Glasnost Defense Foundation, a Russian human rights organization
• Global Development Finance, an economic database
• Great Dun Fell, a radar station in England
• Growth differentiation factor
• Guardia di Finanza, an Italian law enforcement agency
• Guduf-Gava language
• Guides de France, a French scouting organization
• Guyana Defence Force

• Greek Left
• Greek legends
• Greek letter organization
• Greek letter society
• Greek-Libyan relations
• Greek Life at Florida Atlantic University
• Greek Life at Florida International University
• Greek Life at Florida State University
• Greek life at Georgia Tech
• Greek Life at the University of Central Florida
• Greek Life at the University of Florida
• Greek Life at the University of South Florida
• Greek Life at the University of West Florida
• Greek Life at UWA
• Greek life (disambiguation)
• Greek ligature
• Greek Line
• Greek Literature
• Greek - Lithuanian relations
• Greek Love
• Greek-Luxembourg relations
• Greek Macedonian
• Greek-Macedonian
• Greek Macedonian diaspora
• Greek mainland