Great Sandy may refer to:

• Great Sandy Desert, Western Australia
• High Desert (Oregon), United States, called Great Sandy Desert in the 19th century
• Great Sandy Island (Western Australia)
• Fraser Island, Australia, known for a short period as Great Sandy Island
• Great Sandy Strait, Australia

• Ontario provincial highway 538
• Ontario provincial highway 548
• Ontario provincial highway 550
• Ontario provincial highway 553
• Ontario provincial highway 563
• Ontario provincial highway 58
• Ontario provincial highway 599
• Ontario provincial highway 6
• Ontario provincial highway 60
• Ontario provincial highway 61
• Ontario provincial highway 62
• Ontario provincial highway 638
• Ontario provincial highway 64
• Ontario provincial highway 644
• Ontario provincial highway 670
• Ontario provincial highway 69
• Ontario provincial highway 7
• Ontario provincial highway 71
• Ontario provincial highway 72
• Ontario provincial highway 8
• Ontario provincial highway 89
• Ontario provincial highway 9
• Ontario Provincial Junior A Hockey League (1972–87)
• Ontario Provincial Referendum,2007
• Ontario provincial spending, 2004