Michael or Mike Joyce may refer to:

• Michael Joyce (writer) (born 1945), American author and professor of English
• Michael Joyce (tennis) (born 1973), American tennis player
• Michael S. Joyce (1942–2006), American conservative activist
• Michael T. Joyce (born 1949), judge of the Pennsylvania Superior Court
• Michael Joyce (MP) (1851–1941), Member of Parliament for Limerick City, 1900–1918
• Mike Joyce (musician) (born 1963), English drummer for The Smiths
• Mike Joyce (baseball) (born 1941), former relief pitcher in Major League Baseball
• Mike Joyce (golfer) (born 1939), American professional golfer

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