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词条 Panuramine
释义

  1. See also

  2. References

{{Drugbox
| IUPAC_name = N-{[1-(naphthalen-2-ylmethyl)piperidin-4-yl]carbamoyl}benzamide
| image = Panuramine.svg
| width = 225
| tradename =
| pregnancy_category =
| legal_status =
| routes_of_administration =
| bioavailability =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 80349-58-2
| CAS_supplemental =
{{CAS|80349-03-7}} (HCl)
| ATC_prefix = None
| ATC_suffix =
| PubChem = 72002
| ChemSpiderID = 65002
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 1UWS3T8EAB
| C=24 | H=25 | N=3 | O=2
| molecular_weight = 387.47 g/mol
| smiles = O=C(c1ccccc1)NC(=O)NC4CCN(Cc2ccc3c(c2)cccc3)CC4
}}Panuramine (Wy-26,002) is an antidepressant which was synthesized in 1981 by Wyeth.[1] It acts as a potent and selective serotonin reuptake inhibitor (SSRI).[2] It was never marketed.[1]

See also

  • Selective serotonin reuptake inhibitor

References

1. ^{{cite book | author = David J. Triggle | title = Dictionary of pharmacological agents | publisher = Chapman & Hall | location = London | year = 1997 | pages = | isbn = 0-412-46630-9 | oclc = | doi = | url = https://books.google.com/books?id=A0THacd46ZsC&lpg=PA1519&dq=panuramine&pg=PA1519#v=onepage&q=panuramine&f=false}}
2. ^{{cite journal |vauthors=Blurton PA, Broadhurst AM, Cross JA, Ennis C, Wood MD, Wyllie MG | title = Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine in the brain of the rat | journal = Neuropharmacology | volume = 23 | issue = 9 | pages = 1049–52 |date=September 1984 | pmid = 6514142 | doi = 10.1016/0028-3908(84)90127-8| url = }}
{{Antidepressants}}{{Monoamine reuptake inhibitors}}

5 : Benzamides|Naphthalenes|Piperidines|Selective serotonin reuptake inhibitors|Ureas

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