词条 | Panuramine |
释义 |
| IUPAC_name = N- | image = Panuramine.svg | width = 225 | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number = 80349-58-2 | CAS_supplemental = {{CAS|80349-03-7}} (HCl) | ATC_prefix = None | ATC_suffix = | PubChem = 72002 | ChemSpiderID = 65002 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 1UWS3T8EAB | C=24 | H=25 | N=3 | O=2 | molecular_weight = 387.47 g/mol | smiles = O=C(c1ccccc1)NC(=O)NC4CCN(Cc2ccc3c(c2)cccc3)CC4 }}Panuramine (Wy-26,002) is an antidepressant which was synthesized in 1981 by Wyeth.[1] It acts as a potent and selective serotonin reuptake inhibitor (SSRI).[2] It was never marketed.[1] See also
References1. ^1 {{cite book | author = David J. Triggle | title = Dictionary of pharmacological agents | publisher = Chapman & Hall | location = London | year = 1997 | pages = | isbn = 0-412-46630-9 | oclc = | doi = | url = https://books.google.com/books?id=A0THacd46ZsC&lpg=PA1519&dq=panuramine&pg=PA1519#v=onepage&q=panuramine&f=false}} {{Antidepressants}}{{Monoamine reuptake inhibitors}}2. ^{{cite journal |vauthors=Blurton PA, Broadhurst AM, Cross JA, Ennis C, Wood MD, Wyllie MG | title = Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine in the brain of the rat | journal = Neuropharmacology | volume = 23 | issue = 9 | pages = 1049–52 |date=September 1984 | pmid = 6514142 | doi = 10.1016/0028-3908(84)90127-8| url = }} 5 : Benzamides|Naphthalenes|Piperidines|Selective serotonin reuptake inhibitors|Ureas |
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