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词条 Trichosanthin
释义

  1. References

  2. External links

Trichosanthin is a ribosome-inactivating protein.[1][2]

It is derived from Trichosanthes kirilowii.[3]

It is also an abortifacient.[4]

References

1. ^{{cite journal |vauthors=Too PH, Ma MK, Mak AN, etal |title=The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome |journal=Nucleic Acids Res. |volume=37 |issue=2 |pages=602–10 |date=February 2009 |pmid=19073700 |doi=10.1093/nar/gkn922 |url=http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=19073700 |pmc=2632931}}
2. ^{{cite journal |vauthors=Shaw PC, Lee KM, Wong KB |title=Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties |journal=Toxicon |volume=45 |issue=6 |pages=683–9 |date=May 2005 |pmid=15804517 |doi=10.1016/j.toxicon.2004.12.024 |url=http://linkinghub.elsevier.com/retrieve/pii/S0041-0101(05)00050-4}}
3. ^{{cite journal |vauthors=Zhao J, Ben LH, Wu YL, etal |title=Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors |journal=J. Exp. Med. |volume=190 |issue=1 |pages=101–11 |date=July 1999 |pmid=10429674 |pmc=2195565 |doi= 10.1084/jem.190.1.101|url=http://www.jem.org/cgi/pmidlookup?view=long&pmid=10429674}}
4. ^{{cite journal |vauthors=Li MX, Yeung HW, Pan LP, Chan SI|authorlink4=Sunney Chan |title=Trichosanthin, a potent HIV-1 inhibitor, can cleave supercoiled DNA in vitro |journal=Nucleic Acids Res. |volume=19 |issue=22 |pages=6309–12 |date=November 1991 |pmid=1659689 |pmc=329144 |doi= 10.1093/nar/19.22.6309|url=http://nar.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=1659689}}

External links

  • {{MeshName|Trichosanthin}}
{{pharmacology-stub}}

2 : Proteins|Ribosome-inactivating proteins

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