“ZNF217”的意思、由来-开放百科全书

ZNF217 can attenuate apoptotic signals resulting from telomere dysfunction and may promote neoplastic transformation and later stages of malignancy.^[3] Znf217 was shown to be a prognostic biomarker and therapeutic target during breast cancer progression.^[4]

References

1. ^{{cite journal | vauthors = Collins C, Rommens JM, Kowbel D, Godfrey T, Tanner M, Hwang SI, Polikoff D, Nonet G, Cochran J, Myambo K, Jay KE, Froula J, Cloutier T, Kuo WL, Yaswen P, Dairkee S, Giovanola J, Hutchinson GB, Isola J, Kallioniemi OP, Palazzolo M, Martin C, Ericsson C, Pinkel D, Albertson D, Li WB, Gray JW | title = Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 15 | pages = 8703–8 | date = Jul 1998 | pmid = 9671742 | pmc = 21140 | doi = 10.1073/pnas.95.15.8703 }}
2. ^{{cite web | title = Entrez Gene: ZNF217 zinc finger protein 217| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7764| accessdate = }}
3. ^{{cite journal | vauthors = Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C | title = ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction | journal = Human Molecular Genetics | volume = 14 | issue = 21 | pages = 3219–25 | date = Nov 2005 | pmid = 16203743 | doi = 10.1093/hmg/ddi352 }}
4. ^{{cite journal | vauthors = Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z|authorlink19=Howard Y. Chang | title = The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression | journal = Cancer Discovery | volume = 2 | issue = 7 | pages = 638–51 | date = Jul 2012 | pmid = 22728437 | pmc = 3546490 | doi = 10.1158/2159-8290.CD-12-0093 | url = http://cancerdiscovery.aacrjournals.org/content/2/7/638.long }}

Further reading

{{cite journal | vauthors = Quinlan KG, Verger A, Yaswen P, Crossley M | title = Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad | journal = Biochimica et Biophysica Acta | volume = 1775 | issue = 2 | pages = 333–40 | date = Jun 2007 | pmid = 17572303 | doi = 10.1016/j.bbcan.2007.05.001 }}

{{cite journal | vauthors = Kallioniemi A, Kallioniemi OP, Piper J, Tanner M, Stokke T, Chen L, Smith HS, Pinkel D, Gray JW, Waldman FM | title = Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 91 | issue = 6 | pages = 2156–60 | date = Mar 1994 | pmid = 8134364 | pmc = 43329 | doi = 10.1073/pnas.91.6.2156 }}

{{cite journal | vauthors = Collins C, Rommens JM, Kowbel D, Godfrey T, Tanner M, Hwang SI, Polikoff D, Nonet G, Cochran J, Myambo K, Jay KE, Froula J, Cloutier T, Kuo WL, Yaswen P, Dairkee S, Giovanola J, Hutchinson GB, Isola J, Kallioniemi OP, Palazzolo M, Martin C, Ericsson C, Pinkel D, Albertson D, Li WB, Gray JW | title = Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 15 | pages = 8703–8 | date = Jul 1998 | pmid = 9671742 | pmc = 21140 | doi = 10.1073/pnas.95.15.8703 }}

{{cite journal | vauthors = Nonet GH, Stampfer MR, Chin K, Gray JW, Collins CC, Yaswen P | title = The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells | journal = Cancer Research | volume = 61 | issue = 4 | pages = 1250–4 | date = Feb 2001 | pmid = 11245413 | doi = }}

{{cite journal | vauthors = Hakimi MA, Dong Y, Lane WS, Speicher DW, Shiekhattar R | title = A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes | journal = The Journal of Biological Chemistry | volume = 278 | issue = 9 | pages = 7234–9 | date = Feb 2003 | pmid = 12493763 | doi = 10.1074/jbc.M208992200 }}

{{cite journal | vauthors = Weiss MM, Snijders AM, Kuipers EJ, Ylstra B, Pinkel D, Meuwissen SG, van Diest PJ, Albertson DG, Meijer GA | title = Determination of amplicon boundaries at 20q13.2 in tissue samples of human gastric adenocarcinomas by high-resolution microarray comparative genomic hybridization | journal = The Journal of Pathology | volume = 200 | issue = 3 | pages = 320–6 | date = Jul 2003 | pmid = 12845628 | doi = 10.1002/path.1359 }}

{{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = Aug 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}

{{cite journal | vauthors = Shimada M, Imura J, Kozaki T, Fujimori T, Asakawa S, Shimizu N, Kawaguchi R | title = Detection of Her2/neu, c-MYC and ZNF217 gene amplification during breast cancer progression using fluorescence in situ hybridization | journal = Oncology Reports | volume = 13 | issue = 4 | pages = 633–41 | date = Apr 2005 | pmid = 15756435 | doi = 10.3892/or.13.4.633 }}

{{cite journal | vauthors = Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C | title = ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction | journal = Human Molecular Genetics | volume = 14 | issue = 21 | pages = 3219–25 | date = Nov 2005 | pmid = 16203743 | doi = 10.1093/hmg/ddi352 }}

{{cite journal | vauthors = Quinlan KG, Nardini M, Verger A, Francescato P, Yaswen P, Corda D, Bolognesi M, Crossley M | title = Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins | journal = Molecular and Cellular Biology | volume = 26 | issue = 21 | pages = 8159–72 | date = Nov 2006 | pmid = 16940172 | pmc = 1636751 | doi = 10.1128/MCB.00680-06 }}

{{cite journal | vauthors = Cowger JJ, Zhao Q, Isovic M, Torchia J | title = Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence | journal = Oncogene | volume = 26 | issue = 23 | pages = 3378–86 | date = May 2007 | pmid = 17130829 | doi = 10.1038/sj.onc.1210126 }}

Function

See also

References

Further reading

External links