词条 | Airborne disease |
释义 |
An airborne disease is any disease that is caused by pathogens that can be transmitted through the air. Such diseases include many of considerable importance both in human and veterinary medicine. The relevant pathogens may be viruses, bacteria, or fungi, and they may be spread through breathing, talking, coughing, sneezing, raising of dust, spraying of liquids, toilet flushing or any activities which generates aerosol particles or droplets. Human airborne diseases do not include conditions caused by air pollution such as Volatile Organic Compounds (VOCs), gases and any airborne particles, though their study and prevention may help inform the science of airborne disease transmission.{{cn|date=December 2017}} OverviewAirborne diseases include any that are caused via transmission through the air. Many airborne diseases are of great medical importance. The pathogens transmitted may be any kind of microbe, and they may be spread in aerosols, dust or liquids. The aerosols might be generated from sources of infection such as the bodily secretions of an infected animal or person, or biological wastes such as accumulate in lofts, caves, garbage and the like. Such infected aerosols may stay suspended in air currents long enough to travel for considerable distances, though the rate of infection decreases sharply with the distance between the source and the organism infected. Airborne pathogens or allergens often cause inflammation in the nose, throat, sinuses and the lungs. This is caused by the inhalation of these pathogens that affect a person's respiratory system or even the rest of the body. Sinus congestion, coughing and sore throats are examples of inflammation of the upper respiratory air way due to these airborne agents. Air pollution plays a significant role in airborne diseases which is linked to asthma. Pollutants are said to influence lung function by increasing air way inflammation.[1] Many common infections can spread by airborne transmission at least in some cases, including: Anthrax (inhalational), Chickenpox, Influenza, Measles, Smallpox, Cryptococcosis, and Tuberculosis. Airborne diseases can also affect non-humans. For example, Newcastle disease is an avian disease that affects many types of domestic poultry worldwide which is transmitted via airborne contamination.[2] Often, airborne pathogens or allergens cause inflammation in the nose, throat, sinuses, and the upper airway lungs. Upper airway inflammation causes coughing congestion, and sore throat. This is caused by the inhalation of these pathogens that affect a person's respiratory system or even the rest of the body. Sinus congestion, coughing and sore throats are examples of inflammation of the upper respiratory air way due to these airborne agents. SourcesAirborne disease is transmitted as both small, dry particles, and as larger liquid droplets.[3] TransmissionAirborne transmission of disease depends on several physical variables endemic to the infectious particle. Environmental factors influence the efficacy of airborne disease transmission; the most evident environmental conditions are temperature and relative humidity. The sum of all the factors that influence temperature and humidity, either meteorological (outdoor) or human (indoor), as well as other circumstances influencing the spread of the droplets containing the infectious particles, as winds, or human behavior, sum up the factors influencing the transmission of airborne diseases.
UV is harmful to both viruses and bacteria. UV incidence can determine the survival of the infectious particles, so that in those territories with a higher average of sunshine daily hours, and closer to the equator, some particles lose their infectious ability. Infectious particles show an increased survival in the presence of UV light at higher relative humidity levels. It is thought to be due to the protective effect of larger particle sizes, as evaporation would be less at these higher RH levels, showing a protective effect of a thicker water coat.[9] After isolated events, as tropical storms, has been determined that firstly the quantity of fungal spores is decreased, but a few days later, an exponentially increased number of spores is found, compared to normal conditions.[10]
Nearness to large sources of water as rivers and lakes can be a cause of some outbreaks of airborne diseases, after changes in local watershed.[8] Poor sewage systems are usually found in poor countries, especially in the rural areas, and can determine the proliferation of infectious bacteria, that once infecting animal or humans can be transmitted throughout the air. Working conditions, can also settle infectious airborne diseases. At indoor environments, temperature and relative humidity are mainly affected by HVAC systems (heating, ventilation and air conditioning).[11] Inadequate ventilation is implicated in the airborne transmission of respiratory viruses.[4] Poor maintenance or defects on those systems can foster the conditions for airborne infections.[12] For instance, a poor maintenance of air conditioning systems, can lead to an outbreak of Legionella (mainly Legionella pneumophila), that will spread among the population of the building (workers), before the finding of the focal point.[13] In hospitals, isolation of patients sick of infectious diseases has to be added as a factor, which is noticeable in poor regions, where lack of resources facilitates the spread of infectious diseases.{{cn|date=July 2017}} PreventionSome ways to prevent airborne diseases include washing hands, using appropriate hand disinfection, getting regular immunizations against diseases believed to be locally present, wearing a respirator and limiting time spent in the presence of any patient likely to be a source of infection.[14] Exposure to a patient or animal with an airborne disease does not guarantee receiving the disease. Because of the changes in host immunity and how much the host was exposed to the particles in the air makes a difference to how the disease affects the body.[14] Antibiotics are not prescribed for patients to control viral infections. They may however be prescribed to a flu patient for instance, to control or prevent bacterial secondary infections. They also may be used in dealing with air-borne bacterial primary infections, such as pneumonic plague.[15] Additionally the Centers for Disease Control and Prevention (CDC) has told consumers about vaccination and following careful hygiene and sanitation protocols for airborne disease prevention.[16] Consumers also have access to preventive measures like UV Air purification devices that FDA and EPA-certified laboratory test data has verified as effective in inactivating a broad array of airborne infectious diseases.[17] Many public health specialists recommend social distancing to reduce the transmission of airborne infections.[18] See also
References1. ^{{cite web|url=http://www.nutramed.com/Air/airborne_diseases.htm |title=Airborne diseases |deadurl=yes |accessdate=21 May 2013 |archiveurl=https://web.archive.org/web/20120628073116/http://www.nutramed.com/Air/airborne_diseases.htm |archivedate=28 June 2012 }} {{DEFAULTSORT:Airborne Disease}}2. ^{{cite journal|last=Mitchell|first=Bailey W.|author2=King, Daniel J.|title=Effect of Negative Air Ionization on Airborne Transmission of Newcastle Disease Virus|journal=Avian Diseases|date=October–December 1994|volume=38|issue=4|pages=725–732|jstor=1592107 |doi=10.2307/1592107}} 3. ^{{Cite web|url=https://www.cdc.gov/infectioncontrol/pdf/guidelines/isolation-guidelines-H.pdf|title=Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings (2007)|last=Siegel JD, Rhinehart E, Jackson M, Chiarello L, and the Healthcare Infection Control Practices Advisory Committee|date=|website=CDC|archive-url=|archive-date=|dead-url=|access-date=2019-02-07}} 4. ^1 {{cite journal |title=Environmental Factors Affecting the Transmission of Respiratory Viruses |pmc=3311988 | pmid=22440971 |doi=10.1016/j.coviro.2011.12.003 |volume=2 |issue=1 |year=2012 |journal=Curr Opin Virol |pages=90–5 |vauthors=Pica N, Bouvier NM }} 5. ^1 {{cite journal |title=Variation assessment of airborne Alternaria and Cladosporium spores at different bioclimatical conditions.|pmid=15912938 | volume=109 |issue=4 |vauthors=Rodríguez-Rajo FJ, Iglesias I, Jato V |journal=Mycol Res |pages=497–507 |doi=10.1017/s0953756204001777 |year=2005|citeseerx=10.1.1.487.177 }} 6. ^{{cite journal |title=Atmospheric concentrations of Cladosporium spp. and Alternaria spp. spores in Zagreb (Croatia) and effects of some meteorological factors.|pmid=15627341 | volume=11 |issue=2 |vauthors=Peternel R, Culig J, Hrga I |journal=Ann Agric Environ Med |pages=303–7 |year=2004}} 7. ^{{cite journal | vauthors = Sabariego S, Díaz de la Guardia C, Alba F | title = The effect of meteorological factors on the daily variation of airborne fungal spores in Granada (southern Spain) | journal = Int J Biometeorol | volume = 44 | issue = 1 | pages = 1–5 | date = May 2000 | pmid = 10879421 | doi = 10.1007/s004840050131}} 8. ^1 {{cite journal |title=Association of climatic factors with infectious diseases in the Arctic and subarctic region – a systematic review|pmc=4079933 | pmid=24990685 |volume=7 |year=2014 |journal=Glob Health Action |pages=24161 |vauthors=Hedlund C, Blomstedt Y, Schumann B |doi=10.3402/gha.v7.24161}} 9. ^1 {{cite journal |title=The effect of environmental parameters on the survival of airborne infectious agents|pmc=2843949 | pmid=19773291 |doi=10.1098/rsif.2009.0227.focus |volume=6 Suppl 6 |year=2009 |journal=J R Soc Interface |pages=S737–46 |author=Tang JW}} 10. ^{{cite journal |title=An environmental assessment of mold concentrations and potential mycotoxin exposures in the greater Southeast Texas area.|pmid=14672314 | volume=38 |issue=12 |vauthors=Khan NN, Wilson BL |journal=J Environ Sci Health a Tox Hazard Subst Environ Eng |pages=2759–72 |year=2003|doi=10.1081/ESE-120025829 }} 11. ^{{cite journal | vauthors = Fernstrom A, Goldblatt M | title = Aerobiology and its role in the transmission of infectious diseases | journal = J Pathog | volume = 2013 | issue = | pages = 493960 | date = 2013 | pmid = 23365758 | pmc = 3556854 | doi = 10.1155/2013/493960 }} 12. ^{{cite web|url=http://www.genesisair.com/AirborneHealthcareAquiredInfectionsHAI.htm|title=Aerosolization 's Roll in Transmission of Healthcare Acquired Conditions|accessdate=12 April 2015|archive-url=https://web.archive.org/web/20150609170117/http://www.genesisair.com/AirborneHealthcareAquiredInfectionsHAI.htm|archive-date=9 June 2015|dead-url=yes|df=dmy-all}} 13. ^{{cite web |url=https://www.nlm.nih.gov/medlineplus/ency/article/000616.htm|title=Legionnaire disease|accessdate=12 April 2015}} 14. ^1 {{cite book |last=American Academy of Orthopaedic Surgeons (AAOS) |year=2011 |publisher=Jones & Barlett Publishers |pages=2 |url=https://books.google.com/?id=8hbEOpBtBJIC&printsec=frontcover&dq=books+airborne+disease |title=Bloodborne and Airborne Pathogens |accessdate=21 May 2013|isbn=9781449668273 }} 15. ^{{cite book |author1=Laura Ester Ziady |author2=Nico Small |title=Prevent and Control Infection: Application Made Easy |year=2006 |publisher=Juta and Company Ltd. |pages=119–120 |url=https://books.google.com/books?id=kSKwP3v99dYC&pg=PA119 |accessdate=21 May 2013|isbn=9780702167904 }} 16. ^{{cite web|url=https://www.cdc.gov/vaccines/vpd-vac/|title=Redirect - Vaccines: VPD-VAC/VPD menu page|publisher=|date=2019-02-07}} 17. ^{{cite web |url=https://www.rxair.com/wp-content/themes/rx-wp-amz/lab-results/Eco-RX_Inc_6-13-2007_Rpt_Reprint.pdf |title=Chamber Test Analysis on Eco-RX Inc. Model 400 Air Purifier |accessdate=4 May 2007}} 18. ^{{cite journal | vauthors = Glass RJ, Glass LM, Beyeler WE, Min HJ | title = Targeted social distancing design for pandemic influenza | journal = Emerging Infect. Dis. | volume = 12 | issue = 11 | pages = 1671–81 | date = November 2006 | pmid = 17283616 | pmc = 3372334 | doi = 10.3201/eid1211.060255 }} 1 : Diseases and disorders |
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