| 词条 | Drew Endy |
| 释义 |
| name = | image = Drew Endy in 2009.jpg | image_size = | alt = | caption = | birth_date = {{Birth year and age|1970}} | birth_place = | death_date = | death_place = | resting_place = | resting_place_coordinates = | residence = | citizenship = | nationality = | fields = Synthetic biology | workplaces = Stanford University Massachusetts Institute of Technology Dartmouth College | alma_mater = Dartmouth College | thesis_title = Development and application of a genetically-structured simulation for bacteriophage T7 | thesis_url = http://search.proquest.com/docview/304348966 | thesis_year = 1997 | doctoral_advisor = John Yin[1] | academic_advisors = | doctoral_students = | notable_students = | known_for = | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = | signature = | signature_alt = | website = {{URL|https://twitter.com/DrewEndy}} {{URL|http://openwetware.org/wiki/Endy_Lab}} {{URL|http://engineering.stanford.edu/profile/endy}} | footnotes = | spouse = Christina Smolke[2] }}Andrew (Drew) David Endy (born 1970) is a synthetic biologist and Tenured Professor of bioengineering at Stanford University, California.[3][4][5][6][7][8][9] EducationEndy received his PhD from Dartmouth College in 1997 for his work on genetic engineering using T7 phage.[10] ResearchEndy was a junior fellow for 3 years and later an Assistant Professor in the Department of Biological Engineering at MIT. With Thomas Knight,[11] Gerald Jay Sussman, Randy Rettberg, and other researchers at MIT, Endy is working on synthetic biology and the engineering of standardized biological components, devices, and parts, collectively known as BioBricks.[12] Endy is one of several founders of the Registry of Standard Biological Parts, and invented an abstraction hierarchy for integrated genetic systems. Endy is also known for his opposition to limited ownership and support of free access to genetic information. He has been one of the early promoters of open source biology, and helped start the Biobricks Foundation, a not-for-profit organization that will work to support open-source biology. He was also a co-founder of the now defunct Codon Devices, a biotechnology startup company that aimed to commercialize synthetic biology. In his 2009 book, Denialism How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives,[13] Michael Specter called Endy ‘synthetic biology’s most compelling evangelist’ as he is persistent on discussing the prospects and dangers of synthetic biology on nearly any forum. According to Endy, the prospects of synthetic biology will allow "programming" living organisms in the same way a computer scientist program a software and computer, designing and making a disposable biological system and a manufacturing platform, even one’s own offspring or own copy with improved traits such as to prevent occurrence of disease, and bypassing evolution. The dangers lie in the unknown things that this technology will produce, who will control the technology, pay for it, the ethical and cultural impact, the safety issues and how the whole value system work. Endy is reflective and engaged in the possible risks of this field. He advocates dialogue and a serious discussion on the ‘contract’ on engineering biology with the society. It should be a national strategic priority on advancing the potential benefits of the synthetic biology technology, while accepting that risk is inevitable rather than fixating on theoretical risk. In March 2013, heading a team of researchers that had created the biological equivalent of a transistor, which they dubbed a "transcriptor". The invention was the final of the three components necessary to build a fully functional biocomputer - data storage, information transmission, and a basic system of logic.[14] Dr. Endy continues, to this day, to pursue the perfection of his formulation for Green Pi ale. Early clinical trials have indicated profound impact on cognitive function.{{Citation needed|date=February 2016}} References1. ^{{Cite journal | last1 = Endy | first1 = D. | last2 = Kong | first2 = D. | last3 = Yin | first3 = J. | doi = 10.1002/(SICI)1097-0290(19970720)55:2<375::AID-BIT15>3.0.CO;2-G | title = Intracellular kinetics of a growing virus: A genetically structured simulation for bacteriophage T7 | journal = Biotechnology and Bioengineering | volume = 55 | issue = 2 | pages = 375–389 | year = 1997 | pmid = 18636496 | pmc = }} 2. ^{{Cite journal| title = 365 days: Nature’s 10 | doi = 10.1038/528459a| journal = Nature | volume = 528| pages = 459–467| year = 2015| url = http://www.nature.com/news/365-days-nature-s-10-1.19018| pmc = }} 3. ^{{Cite journal | last1 = Endy | first1 = D. | title = Foundations for engineering biology | doi = 10.1038/nature04342 | journal = Nature | volume = 438 | issue = 7067 | pages = 449–453 | year = 2005 | pmid = 16306983 | pmc = }} 4. ^{{Cite journal | last1 = Colman-Lerner | first1 = A. | last2 = Gordon | first2 = A. | last3 = Serra | first3 = E. | last4 = Chin | first4 = T. | last5 = Resnekov | first5 = O. | last6 = Endy | first6 = D. | last7 = Gustavo Pesce | first7 = C. | last8 = Brent | first8 = R. | doi = 10.1038/nature03998 | title = Regulated cell-to-cell variation in a cell-fate decision system | journal = Nature | volume = 437 | issue = 7059 | pages = 699–706 | year = 2005 | pmid = 16170311 | pmc = }} 5. ^{{Cite journal | last1 = Endy | first1 = D. | last2 = Yaffe | first2 = M. B. | doi = 10.1038/426614a | title = Signal transduction: Molecular monogamy | journal = Nature | volume = 426 | issue = 6967 | pages = 614–615 | year = 2003 | pmid = 14668845 | pmc = }} 6. ^{{Cite journal | last1 = Endy | first1 = D. | last2 = Brent | first2 = R. | title = Modelling cellular behaviour | journal = Nature | volume = 409 | issue = 6818 | pages = 391–395 | doi = 10.1038/35053181 | year = 2001 | pmid = 11201753 | pmc = }} 7. ^{{AcademicSearch|2807507}} 8. ^{{DBLP|name=Drew Endy}} 9. ^{{Cite journal | last1 = Canton | first1 = B. | last2 = Labno | first2 = A. | last3 = Endy | first3 = D. | doi = 10.1038/nbt1413 | title = Refinement and standardization of synthetic biological parts and devices | journal = Nature Biotechnology | volume = 26 | issue = 7 | pages = 787–793 | year = 2008 | pmid = 18612302| pmc = }} 10. ^{{cite thesis |degree=PhD |first=Andrew David|last=Endy |title=Development and application of a genetically-structured simulation for bacteriophage T7 |publisher=Dartmouth College |date=1997 |url=http://search.proquest.com/docview/304348966|authorlink=Drew Endy}} 11. ^{{Cite journal | last1 = Shetty | first1 = R. P. | last2 = Endy | first2 = D. | last3 = Knight | first3 = T. F. | title = Engineering BioBrick vectors from BioBrick parts | doi = 10.1186/1754-1611-2-5 | journal = Journal of Biological Engineering | volume = 2 | pages = 5 | year = 2008 | pmid = 18410688 | pmc =2373286 }} 12. ^[https://www.theguardian.com/science/2005/mar/10/science.research From the cells up], The Guardian, 10 March 2005 13. ^{{cite book|last=Specter|first=Michael|authorlink=Michael Specter|title=Denialsim How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives|year=2009|publisher=Penguin Group|isbn=978-1-59420-230-8|pages=242–253}} 14. ^{{cite news|title=This new discovery will finally allow us to build biological computers|author=Robert T. Gonzalez|work=IO9|date=March 29, 2013|url=http://io9.com/this-new-discovery-will-finally-allow-us-to-build-biolo-462867996|accessdate=March 29, 2013}} External links
6 : 1970 births|Living people|Synthetic biologists|Massachusetts Institute of Technology faculty|Bioengineers|Stanford University School of Engineering faculty |
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